I'm running in Windows 10 Pro. Chrome is my default browser.
When I click on the Chrome icon in my taskbar to open it, and then click on any external URL link, for example a link in a Microsoft Teams message, nothing happens. Chrome doesn't open the link.
If I close the browser and then click on the link, it opens a new instance of Chrome and the link comes up, and clicking other links work.
But if I close Chrome and click on the Chrome icon in my taskbar again, it gets back into the bad state where external URL links do not work.
11 Answer
The problem was as follows. In the shortcut to Chrome in the Taskbar, I had gone to Properties > Advanced, and checked the "Run As Administrator" box. That was causing the issue. When I unchecked the box, I had no other issues opening external links in Chrome.